Impedance Analysis

RTCA-Doxo 662

Impedance-based analysis systems, such as the RTCA Cardio xCELLigence (ACEA Biosciences) and the CardioExcyte (Nanion Technologies), enable continous, label-free measurement of cardiomyocyte function. The combination of spontaneously-beating Cor.4U® human iPS cell-derived cardiomyocytes with this non-invasive assay allows researchers to detect drug-induced acute (minutes to hours) and long-term (days to weeks) changes in cell viability and cell contractility within a single experiment in a 96-well format. The online and continuous high-resolution cell monitoring allows for accurate identification of cardiotoxicity and proarrhythmic risk of drug candidates.

cardio-EPlate 320xCELL-Arrhythmia 320

Unique features:

  • Label-free, continous measurement of spontaneously-beating human iPS cell-derived cardiomyocytes.
  • Accurate identification of both structural cardiotoxicity and proarrhythmic risk of drug candidates.
  • Highly standardized cell model in combination with high-resolution cell monitoring to rule out cardiotoxic compounds earlier in discovery.

xCELLigence Cardio Assay Services are offered by Axiogenesis, and Partners. This email address is being protected from spambots. You need JavaScript enabled to view it..

 

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