Smac.4M® cells are single, spindle-shaped, primary-like smooth muscle cells derived from mouse ES cells. They represent a valuable cell system for academic research as well as drug development markets.
Smac.4M® cells are a 100% pure and express a red fluorescent reporter protein (RFP). Contraction of Smac.4M® cells can be induced by e.g. angiotensin II and bradykinin. Smac.4M® cells are easily integrated into high-content screening assays and are validated in various applications.
Advantages of Smac.4M® human iPSC – derived cardiomyocytes:
- Primary-like smooth muscle cells of mouse origin
- Suitable for drug profiling
- Applicable for organ - specific toxicity
Smac.4M® cells have been validated in the following assays and applications:
- Manual patch clamp
- Microlectrode array